Effects of genetic variations in the Adiponectin pathway genes on the risk of colorectal cancer in the Chinese population

Table 3 The genotype distribution of ADIPOQ and ADIPOR1 in CRC patients and controls

Genotypes	Patients, n (%)	Controls, n (%)	OR (95% CI)^a	OR (95% CI)^b	Pvalue^c
rs266729
CC	173(41.79)	243 (43.78)	Reference	Reference	0.705
GC	205 (48.81)	261(47.03)	1.10(0.84,1.44)	1.12(0.85,1.46)
GG	42(10.00)	51(9.19)	1.16(0.74,1.82)	1.18(0.75,1.86)
GC/GG	247(58.81)	312(56.22)	1.12(0.86,1.44)	1.13(0.87,1.46)
rs822395
AA	343(81.67)	440(79.28)	Reference	Reference	0.38
AC	70(16.67)	109(19.64)	0.82(0.59,1.15)	0.81(0.58,1.12)
CC	7(1.67)	6(1.08)	1.50(0.50,4.49)	1.47(0.49,4.46)
AC/CC	77(18.33)	115(20.72)	0.86(0.62,1.18)	0.84(0.61,1.16)
rs822396
AA	344(81.90)	450(81.08)	Reference	Reference	0.82
AG	73(17.38)	99(17.84)	0.97(0.69,1.35)	0.99(0.70,1.38)
GG	3(0.71)	6(1.08)	0.65(0.16,2.63)	0.63(0.16,2.54)
AG/GG	76(18.10)	105(18.92)	0.94(0.68,1.31)	0.96(0.69,1.34)
rs2241766
TT	190(45.24)	278(50.09)	Reference	Reference	0.265
TG	193(45.95)	238(42.88)	1.19(0.91,1.55)	1.18(0.91,1.54)
GG	37(8.81)	39(7.03)	1.39(0.85,2.26)	1.42(0.86,2.32)
TG/GG	230(54.76)	277(49.91)	1.22(0.94,1.57)	1.21(0.94,1.57)
rs1501299
CC	220(52.38)	265(47.75)	Reference	Reference	0.276
AC	160(38.10)	224(40.36)	0.86(0.66,1.13)	0.87(0.66,1.15)
AA	40(9.52)	66(11.89)	0.73(0.47,1.12)	0.95(0.67,1.36)
AC/AA	200(47.62)	290(52.25)	0.83(0.65,1.07)	0.84(0.65,1.09)
rs12733285
CC	386(91.90)	477(85.95)	Reference	Reference	0.004
CT	34(8.10)	78(14.05)	0.54(0.35,0.82)	0.53(0.35,0.81)
TT	0(0.00)	0(0.00)	--	--
CT/TT	34(8.10)	78(14.05)	0.54(0.35,0.82)	0.53(0.35,0.81)
rs1342387
GG	213(50.71)	210(37.84)	Reference	Reference	0
AG	157(37.38)	263(47.39)	0.59(0.44,0.78)	0.59(0.45,0.78)
AA	50(11.90)	82(14.77)	0.60(0.40,0.90)	0.59(0.39,0.89)
AG/AA	207(49.29)	345(62.16)	0.59(0.46,0.77)	0.59(0.46,0.77)

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