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Table 8 Incidence of BRCA1 or BRCA2 mutations among Slovenian families with only breast cancer history (no ovarian cancer) subdivided according to the number of breast cancer cases in the family.

From: The occurrence of germline BRCA1 and BRCA2sequence alterations in Slovenian population

Group

2 breast cancers in family history*

3 breast cancers in family history*

4 breast cancers in family history*

more then 5 breast cancers in family history*

A

9/29 (31%)

5/21 (24%)

7/16 (43%)

7/11 (64%)

C

5/37 (13%)

3/25 (12%)

4/9 (44%)

2/4 (50%)

D

1/10 (10%)

0/6 (0%)

0/5 (0%)

0/0

  1. *number of positive families/number of all tested families in the group (the proportion of positive families). Group A - families with two or more cases of breast cancer including at least two of them diagnosed under the age of 50 and with no ovarian cancer. Group C - families with two or more cases of breast cancer including one case diagnosed before the age of 50 and with no ovarian cancer. Group D - families with two or more cases of breast cancer all of them diagnosed beyond the age of 50 years and with no ovarian cancer.