TT | TM | MM | Pvalue | |
---|---|---|---|---|
Mean (95% CI) | Mean (95% CI) | Mean (95% CI) | ||
n males/n females | 461/500 | 428/417 | 93/101 | - |
Triglycerides (mmol/L) | 1.99 (1.93, 2.06) | 1.87 (1.81, 1.94) | 1.75 (1.63, 1.89) | 0.002 |
Cholesterol (mmol/L) | 4.91 (4.85, 4.96) | 4.84 (4.78, 4.90) | 4.79 (4.66, 4.91) | 0.120 |
LDL-cholesterol (mmol/L) | 2.78 (2.73, 2.82) | 2.77 (2.72, 2.83) | 2.75 (2.65, 2.86) | 0.937 |
HDL-cholesterol (mmol/L) | 1.05 (1.04, 1.07) | 1.05 (1.05, 1.12) | 1.09 (1.05, 1.12) | 0.178 |
BMI (kg/m 2 ) | 35.94 (35.90, 35.97) | 35.89 (35.85, 35.93) | 35.97 (35.89, 36.05) | 0.101 |
Weight (lbs) | 100.71 (100.22, 101.19) | 100.31 (99.80, 100.83) | 101.10 (100.03, 102.18) | 0.331 |
Waist Circumference (cm) | 115.08 (114.61, 115.55) | 114.91 (114.40, 115.41) | 115.77 (114.72, 116.82) | 0.346 |
Glucose (mmol/L) | 8.44 (8.30, 8.59) | 8.32 (8.17, 8.47) | 8.19 (7.89, 8.51) | 0.269 |
HbA1c | 7.22 (7.16, 7.29) | 7.13 (7.02, 7.20) | 7.08 (6.95, 7.23) | 0.067 |
SBP (mm/Hg) | 129.18 (128.06, 130.30) | 128.68 (127.48, 129.88) | 126.85 (124.41, 129.34) | 0.243 |
DBP (mm/Hg) | 69.45 (68.89, 70.01) | 69.15 (68.55, 69.76) | 68.43 (67.20, 69.68) | 0.327 |
Triglyceride (mmol/L) Following removal of E40K Carriers | 1.99 (1.92, 2.06) (n = 889) | 1.88 (1.81, 1.95) (n = 775) | 1.73 (1.60, 1.88) (n = 182) | 0.002 |
Triglycerides (mmol/L) Subjects not taking lipid-lowering medication | 1.95 (1.86, 2.05) (n = 416) | 1.82 (1.74, 1.93) (n = 344) | 1.66 (1.48, 1.85) (n = 75) | 0.01 |