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Table 1 Participant demographics and genotype distributions

From: Serotonin transporter gene polymorphism may be associated with functional dyspepsia in a Japanese population

 

Controls (n = 646)

FD, total (n = 53)

P 2

EPS (n = 39)4

P 2

PDS (n = 42)4

P 2

Age (years)1

45 (19-78)

52 (21-82)

0.002

50 (21-82)

0.021

51 (21-82)

0.015

Sex (male%)

50.5

49.1

0.887

41.0

0.323

52.4

0.874

Smoking (%)

32.7

28.3

0.647

23.1

0.289

31.0

1.000

Drinking (%)

29.6

32.1

0.755

30.8

0.858

33.3

0.604

5-HTTLPR genotype (%)

       

   SS

69.3

56.6

 

61.5

 

50.0

 

   SL

26.9

37.7

 

30.8

 

42.9

 

   LL

3.7

5.7

0.117

7.7

0.257

7.1

0.019

   P for HWE3

0.173

0.889

 

0.405

 

0.746

 
  1. 1Data are shown as median (range).
  2. 2 P vs. controls by Mann-Whitney U-test (for age) or Fisher's exact test (for other variables).
  3. 3 P for deviation from Hardy-Weinberg equilibrium (HWE).
  4. 4Twenty eight subjects are simultaneously classified EPS and PDS phenotype.
  5. FD, functional dyspepsia; EPS, epigastric pain syndrome; PDS, postprandial distress syndrome
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BMC Medical Genetics

ISSN: 1471-2350

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