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Table 4 MTNR1B haplotypes' genotype distribution, means and standard deviations of various phenotypes for GDM

From: Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus

Phenotype

Loci

C/C

C/R

R/R

BMI

ht1

518(22.34 ± 3.70)

904(22.34 ± 3.62)

454(22.35 ± 3.59)

 

ht2

584(22.39 ± 3.64)

896(22.35 ± 3.63)

396(22.28 ± 3.62)

 

ht3

1719(22.31 ± 3.58)

152(22.72 ± 4.04)

5(23.54 ± 6.94)

 

ht4

1788(22.36 ± 3.65)

86(22.16 ± 3.21)

2(19.80 ± 1.41)

AUC_G

ht1

449(438.33 ± 74.35)

757(429.75 ± 79.48)

375(420.39 ± 84.28)

 

ht2

480(420.98 ± 83.23)

753(430.50 ± 78.91)

348(441.20 ± 73.83)

 

ht3

1446(430.46 ± 80.09)

130(425.51 ± 72.41)

5(405.10 ± 75.33)

 

ht4

1516(429.95 ± 79.07)

64(431.35 ± 88.89)

1(361.50)

HOMA_B

ht1

509(225.47 ± 126.01)

898(240.16 ± 144.09)

448(254.96 ± 200.10)

 

ht2

577(251.20 ± 186.38)

889(240.64 ± 143.02)

389(220.51 ± 128.44)

 

ht3

1700(239.45 ± 157.09)

150(242.64 ± 138.61)

5(239.14 ± 23.78)

 

ht4

1768(239.99 ± 157.73)

85(232.89 ± 98.82)

2(280.10 ± 66.75)

HOMA_IR

ht1

512(2.66 ± 1.60)

898(2.58 ± 1.45)

450(2.54 ± 1.50)

 

ht2

579(2.54 ± 1.61)

889(2.59 ± 1.34)

392(2.68 ± 1.68)

 

ht3

1705(2.59 ± 1.46)

150(2.65 ± 1.95)

5(2.58 ± 1.28)

 

ht4

1773(2.60 ± 1.52)

85(2.42 ± 1.16)

2(2.00 ± 0.24)

FPI

ht1

512(12.34 ± 6.48)

898(12.09 ± 5.64)

450(12.00 ± 5.71)

 

ht2

579(11.98 ± 6.12)

889(12.15 ± 5.31)

392(12.35 ± 6.78)

 

ht3

1705(12.11 ± 5.74)

150(12.45 ± 7.54)

5(12.36 ± 4.49)

 

ht4

1773(12.17 ± 5.96)

85(11.51 ± 4.61)

2(10.50 ± 0.71)

FPG

ht1

449(86.46 ± 12.66)

757(85.32 ± 11.89)

375(84.49 ± 13.30)

 

ht2

480(84.49 ± 12.83)

753(85.40 ± 11.82)

348(86.86 ± 13.23)

 

ht3

1446(85.53 ± 12.66)

130(84.65 ± 10.31)

5(82.20 ± 9.36)

 

ht4

1516(85.44 ± 12.50)

64(85.64 ± 11.87)

1(80.00)

  1. C/C, C/R, and R/R indicate major homozygote, heterozygote, and minor homozygote, respectively.
  2. FPI, fasting plasma insulin; FPG, fasting plasma glucose