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Table 2 Allele and genotype distributions of MTNR1B polymorphisms in GDM and control subjects

From: Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus

Loci Genotype RAF N (%) Referent Co-dominant Dominant Recessive
   GDM Controls GDM Controls OR(95%CI) Pcor. OR(95%CI) Pcor. OR(95%CI) Pcor. OR(95%CI) Pcor.
  CC    235(25.9%) 313(32.2%) 1        
  CT    433(47.6%) 455(46.8%) 1.33 0.1 1.3 0.0008 1.44 0.008 1.42 0.03
rs1387153   0.503 0.444    (1.06-1.66)   (1.14-1.49)   (1.17-1.78)   (1.14-1.78)  
  TT    241(26.5%) 204(21.0%) 1.29 0.001       
       (1.13-1.47)        
  CC    217(23.9%) 294(30.4%) 1        
  CG    435(47.9%) 469(48.6%) 1.31 0.2 1.35 0.0001 1.46 0.006 1.54 0.001
rs10830963   0.521 0.453    (1.04-1.65)   (1.18-1.54)   (1.18-1.81)   (1.23-1.92)  
  GG    256(28.2%) 203(21.0%) 1.34 0.0001       
       (1.18-1.53)        
  1. P values were corrected for multiple testing by multiplying the number of tests (10 tests, 2 SNPs × 5 tests (2 referent, co-dominant, dominant and recessive models)) (Bonferroni correction). RAF, risk allele frequency.