Table 2 Allelic and genotypic frequencies of IL-10 gene promoter haplotypes in schizophrenic and healthy males and females
Males | Females | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Control (n = 181) | Schizophrenia (n = 153) | Control (n = 200) | Schizophrenia (n = 88) | |||||||
Allelic frequencies | n | % | n | % | p | n | % | n | % | p |
GCC | 146 | 40.3% | 111 | 36.3% | 0.557 | 167 | 41.8% | 58 | 33.0% | 0.124 |
ACC | 126 | 34.8% | 115 | 37.6% | 134 | 33.5% | 65 | 36.9% | ||
ATA | 90 | 24.9% | 80 | 26.1% | 99 | 24.8% | 53 | 30.1% | ||
Genotypic frequencies | ||||||||||
GCC/GCC | 33 | 18.2% | 23 | 15.0% | 0.382 | 26 | 13.0% | 12 | 13.6% | 0.003* |
GCC/ACC | 48 | 26.5% | 39 | 25.5% | 60 | 30.0% | 20 | 22.7% | ||
GCC/ATA | 32 | 17.7% | 26 | 17.0% | 55 | 27.5% | 14 | 15.9% | ||
ACC/ACC | 28 | 15.5% | 22 | 14.4% | 22 | 11.0% | 16 | 18.2% | ||
ACC/ATA | 22 | 12.2% | 32 | 20.9% | 30 | 15.0% | 13 | 14.8% | ||
ATA/ATA | 18 | 9.9% | 11 | 7.2% | 7 | 3.5% | 13 | 14.8% | ||