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Table 1 Characteristics of the selected sex-steroid synthesizing enzymes and receptors

From: Estrogen and progesterone-related gene variants and colorectal cancer risk in women

Gene Chromosome Covered region (in bp) # of tested SNPs1 LD blocks2
CYP17A1 10q24.3 104562266-104595511 11 2
CYP19A1 15q21.1 49269214-49434085 45 5
HSD17B1 17q11-q21 37943139-37970046 6 2
HSD17B2 16q24.1-q24.2 80608616-80698062 16 4
HSD17B4 5q21 118797197-118889612 7 2
ESR1 6q25.1 151999305-152477851 121 22
ESR2 14q23.2 63750946-63838055 11 2
PGR 11q22-q23 100396881-100529492 25 4
  1. 1. SNPs with Hardy-Weinberg equilibrium and a minor allele frequency of ≥5% in the Women's Health Initiative Observational Cohort (WHI-OS) study Caucasians.
  2. 2. From the WHI-OS Caucasian controls.