Table 7 Association of 37 PRDX6 genotypes and risk of ALI using and additive model in a population of African and European Americans with major trauma
From: Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma
| Â | Â | European Americans | African Americans | ||||||
|---|---|---|---|---|---|---|---|---|---|
SNP | Source | MAF (ALI) | MAF (non-ALI) | Missing Genotype Frequency | p value | MAF (ALI) | MAF (non-ALI) | Missing Genotype Frequency | p value |
hCV1948447 | Tagging | 0.22 | 0.20 | 0.016 | 0.538 | 0.06 | 0.05 | 0.019 | 0.507 |
hCV25599136 | Tagging | 0.00 | 0.00 | 0.161 | NA | 0.03 | 0.03 | 0.230 | 0.842 |
hCV25599144 | Tagging | 0.00 | 0.01 | 0.399 | 0.999 | 0.00 | 0.00 | 0.296 | NA |
hCV9040425 | Tagging | 0.27 | 0.25 | 0.021 | 0.739 | 0.38 | 0.35 | 0.019 | 0.725 |
hCV9040434 | Tagging | 0.25 | 0.24 | 0.407 | 0.838 | 0.31 | 0.29 | 0.307 | 0.537 |
Position23855054 | Sequencing | 0.00 | 0.00 | 0.012 | NA | 0.09 | 0.08 | 0.019 | 0.535 |
Position23855203 | Sequencing | 0.00 | 0.00 | 0.679 | NA | 0.10 | 0.17 | 0.662 | 0.268 |
Position23859396 | Sequencing | 0.00 | 0.00 | 0.012 | NA | 0.04 | 0.02 | 0.019 | 0.302 |
Position23863249 | Sequencing | 0.00 | 0.00 | 0.012 | NA | 0.03 | 0.03 | 0.023 | 0.577 |
PRDX6_171709910 | Sequencing | 0.03 | 0.01 | 0.436 | 0.192 | 0.04 | 0.06 | 0.494 | 0.505 |
PRDX6_171711459 | Sequencing | 0.00 | 0.00 | 0.021 | NA | 0.11 | 0.18 | 0.043 | 0.088 |
PRDX6_171713872 | Sequencing | 0.00 | 0.01 | 0.037 | 0.999 | 0.08 | 0.05 | 0.070 | 0.331 |
PRDX6_171715019 | Sequencing | 0.00 | 0.00 | 0.029 | 0.999 | 0.05 | 0.05 | 0.058 | 0.879 |
PRDX6_171724949 | Sequencing | 0.22 | 0.19 | 0.029 | 0.455 | 0.07 | 0.05 | 0.043 | 0.481 |
rs10753081 | Sequencing | 0.34 | 0.29 | 0.008 | 0.246 | 0.37 | 0.34 | 0.000 | 0.676 |
rs2000 | Tagging | 0.05 | 0.05 | 0.045 | 0.966 | 0.02 | 0.02 | 0.031 | 0.793 |
rs33942654 | Sequencing | 0.23 | 0.20 | 0.021 | 0.321 | 0.34 | 0.29 | 0.054 | 0.138 |
rs34129563 | Sequencing | 0.07 | 0.03 | 0.021 | 0.080 | 0.01 | 0.01 | 0.039 | 0.559 |
rs34619706 | Sequencing | 0.08 | 0.08 | 0.037 | 0.900 | 0.03 | 0.01 | 0.047 | 0.287 |
rs35244306 | Sequencing | 0.00 | 0.01 | 0.021 | 0.999 | 0.11 | 0.08 | 0.039 | 0.517 |
rs35749242 | Sequencing | 0.00 | 0.01 | 0.021 | 0.999 | 0.08 | 0.06 | 0.039 | 0.516 |
rs4354572 | Sequencing | 0.00 | 0.00 | 0.354 | NA | 0.11 | 0.17 | 0.358 | 0.251 |
rs4382766 | Sequencing | 0.33 | 0.29 | 0.025 | 0.312 | 0.35 | 0.34 | 0.047 | 0.830 |
rs4916362 | Tagging | 0.34 | 0.29 | 0.021 | 0.308 | 0.35 | 0.32 | 0.019 | 0.670 |
rs57032935 | Sequencing | 0.23 | 0.19 | 0.037 | 0.296 | 0.34 | 0.29 | 0.082 | 0.131 |
rs6671141 | Sequencing | 0.23 | 0.19 | 0.210 | 0.421 | 0.38 | 0.33 | 0.163 | 0.170 |
rs6699179 | Tagging | 0.00 | 0.00 | 0.214 | NA | 0.01 | 0.00 | 0.171 | 0.999 |
rs6702828 | Tagging | 0.00 | 0.00 | 0.012 | NA | 0.01 | 0.00 | 0.027 | 0.778 |
rs6702835 | Sequencing | 0.27 | 0.25 | 0.008 | 0.606 | 0.42 | 0.37 | 0.000 | 0.493 |
rs7314 | Sequencing | 0.27 | 0.25 | 0.045 | 0.666 | 0.34 | 0.30 | 0.078 | 0.571 |
rs7367963 | Tagging | 0.34 | 0.29 | 0.029 | 0.284 | 0.35 | 0.31 | 0.019 | 0.574 |
rs7521536 | Tagging | 0.24 | 0.20 | 0.025 | 0.360 | 0.32 | 0.29 | 0.043 | 0.320 |
rs7529377 | Tagging | 0.24 | 0.20 | 0.016 | 0.331 | 0.28 | 0.26 | 0.027 | 0.321 |
rs7540065 | Sequencing | 0.27 | 0.25 | 0.021 | 0.726 | 0.37 | 0.35 | 0.039 | 0.997 |
rs912767 | Tagging | 0.24 | 0.20 | 0.016 | 0.331 | 0.29 | 0.26 | 0.027 | 0.240 |
rs9425722 | Sequencing | 0.00 | 0.00 | 0.342 | NA | 0.08 | 0.17 | 0.335 | 0.048 |
rs9425725 | Tagging | 0.00 | 0.00 | 0.012 | NA | 0.13 | 0.20 | 0.027 | 0.091 |