Table 3 Distribution of PRNP 310C allele, stratified by PRNP M129V genotypes, and risk of sporadic CJD
PRNPM129V genotype | PRNPSNP | Cases (%) | Controls (%) | OR (95% CI) | P- value* |
|---|---|---|---|---|---|
Methionine/methionine | 310C Carriers | 8 (8.2) | 1 (1.2) | 7.2 (0.9-58.8) | 0.04 |
Non carriers | 90 (91.8) | 81 (98.6) | |||
Methionine/valine | 310C Carriers | 4 (23.5) | 12 (13.0) | 2.1 (0.6-7.3) | 0.27 |
Non carriers | 13 (76.5) | 80 (87.0) | |||
Valine/valine | 310C Carriers | 5 (31.3) | 5 (25.0) | 1.4 (0.3-5.9) | 0.72 |
Non carriers | 11 (68.8) | 15 (75.0) |