CRP polymorphisms and chronic kidney disease in the third national health and nutrition examination survey

BMC Medical Genetics

Table 2 CRP polymorphisms, location and genotype frequencies for all participants by CKD status.

SNP	rs2808630			rs1205			rs1800947*			rs3093058			rs3093066			rs1417938
Location	3' flanking region			3' flanking region			Exon 2			5' flanking region			5' flanking region			Intron 1
Genotypes	AA	AG	GG	GG	AG	AA	GG	CG	CC	AA	AT	TT	CC	AC	AA	AA	AT	TT
*Non-Hispanic Whites*
N	270	221	43	241	236	57	475	**	**	537	5	-	498	9	-	259	239	48
CKD, GFP	50.75	42.68	6.57	46.17	42.19	11.63	93.19	**	**	98.36	1.64	-	97.69	2.31	-	47.44	43.7	8.79
N	867	686	133	694	808	190	1544	**	**	1718	6	-	1610	15	-	851	730	148
No-CKD,GFP	52.13	40.38	7.49	42.16	46.51	11.33	94.43	**	**	99.55	0.45	-	98.94	1.06	-	49.22	42.22	8.56
*Non-Hispanic Blacks*
	rs2808630			rs1205			rs1800947*			rs3093058			rs3093066			rs1417938
N	181	96	8	190	86	9	**	**	-	212	71	8	154	105	15	221	62	**
CKD, GFP	61.45	36.4	2.14	67.06	29.39	3.55	99	**	-	76.01	22.89	1.1	56.35	38.37	5.28	77.75	20.65	**
N	950	323	26	804	397	79	**	**	-	915	356	34	751	443	67	1024	272	21
No-CKD,GFP	72.24	25.42	2.34	62.68	31.26	6.06	99	**	-	69.67	27.66	2.67	60.67	34.12	5.21	77.54	21.75	0.4
*Mexicans Americans*
	rs2808630			rs1205			rs1800947*			rs3093058			rs3093066			rs1417938
N	167	89	11	102	137	31	253	7	-	260	8	**	269	**	**	110	130	24
CKD, GFP	61.12	33.75	5.13	42.21	47.09	10.70	97.66	2.3	-	95.81	3.91	**	99.25	**	**	41.67	49.23	9.1
N	852	434	57	562	621	168	1266	54	-	1348	37	**	1308	**	**	591	616	155
No-CKD,GFP	62.48	33.04	4.48	41.65	45.65	12.7	95.6	4.4	-	97.08	2.92	**	96.59	**	**	43.39	45.23	11.3

** Data user agreement with the CDC does not allow outputs with counts less than 5.
N:number of individuals with the specific genotype. GFP:genotype frequency percent

ISSN: 1471-2350