Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study

BMC Medical Genetics

Table 3 Genotype and Haplotype frequencies for ERAP2, MTHFR, and COMT for African American samples.

African American samples originated from two locations: the University of Pennsylvania Medical Center, PA and Hutzel Women's Hospital, MI. Minor allele frequencies and haplotype frequencies were calculated from control samples only at each location. When comparing locations, no test achieved a significant difference at the 5% level using a Z-test for differences in two independent proportions. SNP, single nucleotide polymorphism. COMT single SNP frequencies are listed first, followed by COMT haplotypes formed by those SNPs. COMT haplotype SNP order: rs6269, rs4633, rs4818, rs4680.

ISSN: 1471-2350