Skip to main content

Table 2 ERAP2 Allelic analysis for maternal and fetal samples with and without preeclampsia.

From: Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study

Population

ERAP2SNP

Genotype (count)

Minor Allele

Frequency

Preeclampsia

Frequency

Controls

P-value

Odds Ratio

(95% C.I.)

Chilean

Maternal

      
 

rs2549782

GG (135)

G

0.330

0.347

0.393

0.925 (0.775, 1.104)

  

TG (477)

     
  

TT (491)

     
 

rs17408150

AA (2)

A

0.044

0.041

0.752

1.069 (0.706, 1.619)

  

TA (89)

     
  

TT (1012)

     
 

Fetal

      
 

rs2549782

GG (124)

G

0.333

0.326

0.751

1.033 (0.865, 1.234)

  

TG (477)

     
  

TT (500)

     
 

rs17408150

AA (0)

A

0.040

0.039

1.000

1.021 (0.665, 1.568)

  

TA (87)

     
  

TT (1014)

     

African

Maternal

      

American

rs2549782

GG (147)

G

0.429

0.391

0.133

1.166 (0.958, 1.420)

  

TG (383)

     
  

TT (295)

     
 

Fetal

      
 

rs2549782

GG (114)

G

0.435

0.369

0.009

1.320 (1.075, 1.619)

  

TG (387)

     
  

TT (268)

     
  1. SNP, single nucleotide polymorphism; C.I., confidence interval. The minor allele (G) of rs2549782 was found significantly more frequently in cases than controls in African American fetal samples.
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us