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Table 2 Summary of T1D association results for the family collections

From: Evidence of association with type 1 diabetes in the SLC11A1 gene region

Variant Number of
families
Number of
informative transmissions
Minor allele frequency (%)
in affected siblings
Minor allele frequency (%)
in unaffected parents
Relative risk
(95% C.I.)
Family
P TDT
rs4674297 G>A NA NA NA NA NA NA
Microsatellite (GT)n 3*>2 1971 1925 27.02 27.06 1.00 (0.92-1.10) 0.87
rs7573065 C>T 2472 610 5.43 5.30 0.92 (0.78-1.08) 0.29
rs2276631 C>T 2707 2587 27.38 27.15 1.00 (0.93-1.08) 0.98
rs3731865 G>C 5010 4876 26.43 26.42 1.00 (0.95-1.06) 0.98
rs2279015 G>A 2523 2862 36.33 36.26 0.94 (0.88-1.02) 0.13
rs17235409 G>A 1859 198 2.05 2.10 0.92 (0.70-1.22) 0.57
rs17235416 TGTG>del 2450 191 1.61 1.65 0.85 (0.64-1.14) 0.28
rs1059823 A>G 2591 2950 39.79 38.81 1.02 (0.95-1.10) 0.56
rs1809231 C>G 2678 3166 42.71 42.14 1.01 (0.94-1.08) 0.78
  1. Number of families with genotyping data for the variants in the SLC11A1 gene region with the respective number of informative transmissions, the relative risk and the P-value from the transmission/disequilibrium test (P TDT). [* Rare microsatellite alleles, with frequency <0.1%, were combined with the common allele 3; 95% C.I. = 95% confidence interval; NA = not available]