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Table 5 Epistatic analyses: odds ratios (OR) and 95% confidence intervals (95% CI) for epistatic effects with p-value < 0.05.

From: The role of the fat mass and obesity associated gene (FTO) in breast cancer risk

Epistatic effect

aModel 1

Model 2

Model 3

rs1477196a:rs9939609a

11.525**

(2.76-48.17)

9.773*

(2.32-41.21)

12.031*

(2.68-53.95)

rs1477196d:rs8047395d

0.0416**

(0.01-0.15)

0.048**

(0.01-0.18)

0.054**

(0.01-0.20)

  1. The term X1:X2 represents interaction between X1 and X2.
  2. *p-value < 0.05, **p-value < 0.001
  3. aModel 1: without covariate; Model 2: adjust for race and age; Model 3: adjust for race, age and BMI
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BMC Medical Genetics

ISSN: 1471-2350

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