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Table 2 Genotypic and allelic frequencies of SNPs AADAT+401C/T and KYNU +715G/A.

From: Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis

Genotype AADAT+401C/T

BM Cases 47 (%)

Controls 54 (%)

OR (95% CI) a

P-value b

CC vs TT d

CC

11 (23)

28 (52)

0.275 (0.150 to 0.507)

<0.0001c

P = 0.021 c

CT

24 (51)

19 (35)

1.933 (1.095 to 3.411)

0.0223c

OR = 0.23 (0.07 to 0.72)

TT

12 (25)

7 (13)

2.231 (1.066 to 4.667)

0.0305c

 

Frequency of T allele

0.51

0.30

2.429 (1.359 to 4.339)

0.0038c

 

Genotype KYNU +715G/A

BM Cases 46 (%)

Controls 52 (%)

OR (95% CI) a

P-value b

GG vs AA d

GG

41 (89)

43 (82)

1.776 (0.7916 to 3.985)

0.1598

P = 0.38

GA

2 (4)

4 (7)

0.5536 (0.1568 to 1.954)

0.3521

OR = 1.91(0.45 to 8.00)

AA

3 (7)

6 (11)

0.6090 (0.2260 to 1.641)

0.3230

 

Frequency of A allele

0.08

0.15

0.4928 (0.1988 to 1.221)

0.1208

 
  1. a ORs and probability values at 95% CI for disease status are shown.
  2. b Values were calculated with the X2-test (two-tailed) comparing controls and case patients.
  3. c Significant P value (P < 0.05).
  4. d Analysis of distribution of the contrasting genotypes. Values calculated with X2-test (two-tailed)