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Table 5 Association of rs16861210, rs17366568, rs2241766, rs6773957 and s2082940 with baseline serum adiponectin levels

From: Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study

    

p/qa

p/qb

rs16861210

GG (224)

GA (12)

AA (1)

  

All

7.76 (7.32-8.22)

10.27 (8.29-12.45)

11.79 (5.33-20.77)

0.029/0.032

0.143/0.495

 

GG (224)

AA, AG (13)

   

All

7.76 (7.32-8.22)

10.38 (8.47-12.48)

 

0.008/0.032

0.201/0.495

rs17366568

GG (169)

GA (59)

AA (9)

  

All

8.40 (7.88-8.94)

6.90 (6.16-7.69)

6.44 (6.48-8.48)

0.003/0.032

0.893/0.840

 

GG (169)

AA, AG (68)

   

All

8.40 (7.88-8.49)

6.84 (6.15-7.58)

 

0.0007/0.032

0.850/0.840

rs2241766

TT (224)

TG (13)

   

All

7.82 (7.38-8.28)

9.70 (7.83-11.76)

 

0.056/0.032

0.020/0.279

Menc

6.45 (5.85-7.08)

12.54 (8.49-17.37)

 

0.003/0.131

 

Womend

8.87 (8.32-9.44)

9.38 (7.30-11.71)

 

0.660/0.092

 

rs6773957

GG (104)

AG (110)

AA (23)

  

All

7.36 (6.74-8.00)

8.12 (7.51-8.75)

9.45 (8.05-10.96)

0.016/0.032

0.711/0.840

 

GG (104)

AA, AG (133)

   

All

7.35 (6.73-8.00)

8.34 (7.77-8.92)

 

0.021/0.032

0.559/0.840

 

AG, GG (214)

AA (23)

   

All

7.76 (7.31-8.22)

9.47 (8.06-10.99)

 

0.022/0.032

0.772/0.840

rs2082940

CC (224)

CT (13)

   

All

7.82 (7.38-8.28)

9.70 (7.83-11.76)

 

0.056/0.032

0.020/0.279

Mene

6.45 (5.85-7.08)

12.54 (8.49-17.37)

 

0.003/0.131

 

Womenf

8.87 (8.32-9.44)

9.38 (7.30-11.71)

 

0.660/0.092

 
  1. Data are expressed as predicted geometric mean (95% CI)- Correction for multiple hypothesis testing was performed with FDR, denoted as q-value.
  2. a adjusted for age, sex and baseline WHR
  3. b sex-genotype interaction
  4. cTT: N = 80, TG: N = 3; dTT: N = 144, TG: N = 10; eCC: N = 80, CT: N = 3; fCC: N = 144, CT: N = 10