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Table 1 The BCL-2 (-938C > A) genotype distribution in patients and controls

From: BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility

Genotype

No. of subjects (%)

Non-adjusted b

Adjusted c

 

Case a

Control a

pvalue

OR

pvalue

OR

AA

19(16.7)

8(7.5)

 

1.00

 

1.00

AC

53(46.5)

53(49.5)

0.062

0.42

0.081

0.44

CC

42(36.8)

46(43.0)

0.043

0.38

0.054

0.40

AC+CC

95(83.3)

99(92.5)

 

1.00

 

1.00

AA

19(16.7)

8(7.5)

0.042

2.47

0.055

2.37

AC+AA

72(63.2)

61(57.0)

 

1.00

 

1.00

CC

42(36.8)

46(43.0)

0.351

0.77

0.358

0.77

AA+CC

61(53.5)

54(50.5)

 

1.00

 

1.00

AC

53(46.5)

53(49.5)

0.651

0.89

0.711

0.90

All

114

107

    
  1. a The χ2 for HWE of case and control group is 0.11 and 1.91 respectively (both p > 0.05).
  2. b Logistic regression model, non-adjusted.
  3. c Logistic regression model, adjusted for diagnostic age.
  4. All statistical tests were two-sided with a significance level of p ≤ 0.05.
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BMC Medical Genetics

ISSN: 1471-2350

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