Table 2 Distribution of sociodemographic characteristics, APOE genotype and APOE allele frequency by ethnic identity
Ethnic identity | 'White' N = 1674 | 'Mixed' N = 260 | 'Black' N = 395 | P value X2 |
|---|---|---|---|---|
Age (mean/SD) | 75.0 (7.0) | 75.7 (7.7) | 74.7 (6.9) | F = 1.7, P = 0.19 |
Male sex (n/%) | 579 (34.6%) | 95 (36.5%) | 118 (29.9%) | X 2 = 4.0, 2df, P = 0.14 |
Education level (n/%) | Â | Â | Â | X 2 = 25.6, 1 df, P < 0.001 |
None | 37 (2.2%) | 7 (2.7%) | 14 (3.6%) | Â |
Some | 344 (20.6%) | 55 (21.2%) | 112 (28.5%) | Â |
Primary | 543 (32.5%) | 87 (33.5%) | 148 (37.7%) | Â |
Secondary | 429 (25.7%) | 62 (23.8%) | 73 (18.6%) | Â |
Tertiary | 317 (19.0%) | 49 (18.8%) | 46 (11.7%) | Â |
APOE Genotype (n/%) | Â | Â | Â | X 2 = 31.4, 1 df, P < 0.001 |
No E4 allele | 1423 (85.0%) | 222 (85.4%) | 298 (75.4%) | Â |
Heterozygous (One e4 allele) | 241 (14.4%) | 32 (12.3%) | 77 (19.5%) | Â |
Homozygous (Two e4 alleles) | 10 (0.6%) | 6 (2.3%) | 20 (5.1%) | Â |
APOE allele frequency | Â | Â | Â | X2 = 42.6, 4 df, P = < 0.001 |
E2 | 0.058 | 0.063 | 0.072 | Â |
E3 | 0.864 | 0.852 | 0.780 | Â |
E4 | 0.078 | 0.085 | 0.148 | Â |