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Table 4 Comparison of serum folate and plasma total homocysteine levels according to MTR and MTHFR genotypes.

From: Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study

  

MTHFR

 
 

MTR

CC

CT

TT

p

 

AA

6.0 ± 2.6

5.6 ± 2.6

4.8 ± 2.1

<.0001

folate

AG

6.0 ± 3.2

5.7 ± 2.1

4.8 ± 2.0

0.0159

(ng/mL)

GG

6.5 ± 3.2

5.3 ± 2.2

4.1 ± 1.8

0.0970

 

AA

10.5 ± 3.3

10.6 ± 3.9

13.8 ± 10.6

<.0001

homocysteine

AG

10.0 ± 2.5

10.9 ± 3.8

13.2 ± 8.8

0.0001

(nmol/mL)

GG

8.9 ± 1.7

10.1 ± 2.2

15.0 ± 6.8

0.0006

  1. N = 1146