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Table 3 Odds ratios and 95% confidence intervals for additive genetic model of MTHFR polymorphism by MTR genotypes with risk of hearing impairment analyzed by generalized estimating equations in cumulative data.

From: Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study

MTR

 

MTHFR

 
  

CC (T = 0)

CT (T = 1)

TT (T = 2)

p

 

N

1933

2475

759

 

AA (wild-type homozygotes)

3370

1

0.7609 (0.6178-0.9372)/T-allele

0.0102

AG (heterozygotes)

1615

1

1.1040 (0.7963-1.5305)/T-allele

0.5528

GG (mutant homozygotes)

182

1

1.3231 (0.6332-2.7649)/T-allele

0.4565

  1. N = 5167
  2. Parenthetical reference shows 95% confidence interval.
  3. [Moderator variable]
  4. age, sex, smoking status, BMI
  5. histories of occupational noise exposure, heart disease, hypertension, and diabetes
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BMC Medical Genetics

ISSN: 1471-2350

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