Skip to main content

Table 3 Effect of rs7903146 genotype on sulfonylurea treatment failure under logistic regression analysis.

From: TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes

Genotype rs7903146 Total Controls
(A1C <7%)
Failure of treatment with sulfonylurea
(A1C≥7%)
Frequency of T-allele
(controls vs. treatment failure)
Additive
P value
OR (95% CI)
  n = 188 n = 91 n = 97   
CC 91 (48.4%) 51 (56.0%) 40 (41.2%)   
CT 78 (41.5%) 33 (36.3%) 45 (46.4%) 0.26/0.36 0.046
1.57 (1.01-2.45)
TT 19 (10.1%) 7 (7.7%) 12 (12.4%)