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Table 4 TGFΒ1 and IREB2 Allele frequencies and odds ratios in Controls and Cases

From: The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

Gene SNP
No.
Locus Major/
Minor
Alleles
Minor
Allele Frequencies
Unadjusted
P-value
Adjusted
P-value*
Adjusted
Odds Ratio**
(95% C. I.)
     Controls COPD
(all
cases)
   
TGFB1 2 rs1800469 C/T 0.32 0.32 0.8852 0.8314 1.02 (0.87, 1.18)
  3 rs1800470 T/C 0.40 0.40 0.9118 0.8901 0.99 (0.86, 1.15)
  4 rs6957 A/G 0.18 0.17 0.2736 0.2590 0.90 (0.74, 1.08)
IREB2 1 rs2568494 G/A 0.35 0.41 <0.0001 0.0005 1.30 (1.12, 1.50)
  2 rs2656069 A/G 0.21 0.16 0.0004 0.0045 0.77 (0.64, 0.92)
  4 rs12593229 G/T 0.39 0.32 <0.0001 0.0013 0.79 (0.68, 0.91)
  1. * p-values adjusted by logistic regression for age, sex, smoking and centre.
  2. ** Adjusted odds ratios are relative to the major Allele, adjusted by logistic regression for age, sex, smoking and centre.