Candidate gene analysis of spontaneous preterm delivery: New insights from re-analysis of a case-control study using case-parent triads and control-mother dyads

Table 8 Significant fetal pathways in spontaneous preterm delivery

		Case-parent triad		Hybrid
KEGG pathway	Pathway Annotation	Single locus	Haplotype	Single locus	Haplotype
hsa04510	Focal Adhesion	0.017	0.019	0.103	0.016
hsa04115	p53 signaling pathway	0.022	0.010	0.054	0.087
hsa01430	Cell Communication	0.024	0.020	0.107	0.012
hsa04512	ECM-receptor interaction	0.024	0.020	0.107	0.012
hsa00361	Gamma-Hexachlorocyclohexane	0.059	0.143	0.016	0.030
hsa00363	Bisphenol A degradation	0.059	0.143	0.016	0.030
hsa04330	Notch signaling pathway	0.061	0.042	0.098	0.112
hsa04210	Apoptosis	0.114	0.211	0.027	0.127
hsa00680	Methane metabolism	0.194	0.261	0.022	0.022
hsa04640	Hematopoietic cell lineage	0.438	0.317	0.083	0.040
hsa04060	Cytokine-cytokine receptor interaction	0.500	0.210	0.080	0.033
hsa04630	Jak-STAT signaling pathway	0.522	0.197	0.043	0.013

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