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Table 7 Significant genes when maternal and fetal alleles are combined

From: Candidate gene analysis of spontaneous preterm delivery: New insights from re-analysis of a case-control study using case-parent triads and control-mother dyads

 

Case-parent triad design

Hybrid design

 

Single locus

Haplotype

Single locus

Haplotype

IGFBP3

0.010

-

0.216

-

GSTP1

0.014

-

0.016

-

COL5A1

0.018

0.104

0.014

0.077

COL5A2

0.022

0.016

0.059

0.031

MTHFD1

0.023

0.051

0.048

0.116

PLG

0.025

0.049

0.121

0.144

MMP8

0.034

0.073

0.041

0.008

IL10RA

0.050

0.028

0.083

0.044

SLC23A1

0.066

0.007

0.549

0.215

PON1

0.082

0.131

0.025

0.120

G0S2

0.085

-

0.022

-

IL1A

0.187

0.276

0.048

0.085

TFPI

0.304

0.599

0.004

0.039

SERPINH1

0.354

0.088

0.216

0.016

TREM1

0.459

0.268

0.106

0.041

SLC6A4

0.525

0.346

0.032

0.045

HSPA6

0.583

0.310

0.050

0.182

IL10RB

0.618

0.584

0.406

0.031

  1. 1 Correction for multiple testing has been performed within each gene.