Figure 1

Location of SNPs genotyped in ALOX5AP , LTA4H and LTB4R in the smokers and linkage disequilibrium (LD) plot. The LD plot shows the LD displayed as D'/LOD in Haploview software. Numerical values shown correspond to D'. A-C. represents the physical location of the SNPs genotyped in ALOX5AP, LTA4H and LTB4R, respectively. Black boxes represent exons and the spaces between represent introns. D. E. and F. represents the LD plot in the smokers (n = 992) for each loci respectively..* represents SNPs that define the haplotype HapA, #which define HapB and ^ which define the haplotype (HapK) previously associated with MI [11, 12].