Table 3 Genotyping results of 19 SNPs in replication stage, sorted by P values under general model.
From: Genome-wide association study identifies PERLD1 as asthma candidate gene
SNPa | Variationb | Chrc | Gened | GWASe | Generalf | Multiplicativeg | OR (95% C.I.)h |
|---|---|---|---|---|---|---|---|
rs2941504 | (G/A) | 17q12 | PERLD1 | 3 | 2.60 × 10-3 | 9.26 × 10-3 | 0.784 (0.653-0.941) |
rs6036630 | (T/C) | 20p11.21 | - | 2 | 8.58 × 10-3 | 6.33 × 10-2 | 1.397 (0.986-1.980) |
rs2304368 | (A/C) | 2q21.3 | R3HDM1 | 2 | 7.06 × 10-2 | 7.70 × 10-2 | 1.808 (0.940-3.475) |
rs12590520 | (T/C) | 14q24.3 | - | 2 | 2.07 × 10-1 | 1.39 × 10-1 | 1.244 (0.944-1.641) |
rs11895665 | (T/C) | 2q37.3 | LRRFIP1 | 2 | 2.47 × 10-1 | 2.76 × 10-1 | 1.194 (0.879-1.620) |
rs10520302 | (T/C) | 4q34.2 | GPM6A | 2 | 2.74 × 10-1 | 9.44 × 10-1 | 0.987 (0.749-1.301) |
rs11225634 | (G/T) | 11q22.3 | DYNC2H1 | 2 | 3.55 × 10-1 | 2.28 × 10-1 | 1.375 (0.855-2.212) |
rs7930326 | (T/C) | 11q23.1 | - | 2 | 4.83 × 10-1 | 2.40 × 10-1 | 0.811 (0.582-1.128) |
rs12601246 | (T/C) | 17p13.3 | SMYD4 | 2 | 5.67 × 10-1 | 5.14 × 10-1 | 1.170 (0.764-1.794) |
rs4738955 | (A/G) | 8q12.3 | NKAIN3 | 2 | 5.76 × 10-1 | 5.89 × 10-1 | 0.847 (0.496-1.445) |
rs8133478 | (G/A) | 21q22.3 | RUNX1 | 2 | 6.10 × 10-1 | 5.28 × 10-1 | 0.844 (0.512-1.391) |
rs9292197 | (C/T) | 5q11.2 | PDE4D | 2 | 7.48 × 10-1 | 8.49 × 10-1 | 1.043 (0.717-1.516) |
rs11904654 | (G/T) | 2p22.3 | LTBP1 | 2 | 8.09 × 10-1 | 6.90 × 10-1 | 0.941 (0.725-1.221) |
rs11948993 | (C/T) | 5p15.31 | - | 2 | 8.29 × 10-1 | 5.94 × 10-1 | 0.916 (0.679-1.235) |
rs6788482 | (A/G) | 3q13.13 | - | 2 | 8.39 × 10-1 | 1.00 | 1.009 (0.746-1.364) |
rs6793110 | (A/G) | 3p14.1 | LRIG1 | 2 | 8.78 × 10-1 | 6.50 × 10-1 | 0.891 (0.570-1.395) |
rs10917042 | (C/T) | 1p36.12 | USP48 | 2 | 8.84 × 10-1 | 6.81 × 10-1 | 0.939 (0.718-1.229) |
rs2268451 | (G/T) | 14q31.1 | TSHR | 2 | 8.95 × 10-1 | 7.49 × 10-1 | 0.944 (0.689-1.292) |
rs5993853 | (T/C) | 22q11.21 | TXNRD2 | 2 | 1.00 | 7.72 × 10-1 | 0.892 (0.503-1.579) |