Table 3 Allele frequencies of SNPs in del22q11 patients (n = 13), non-del patients (n = 199), controls (n = 139) and Han Chinese in 1000 Genome Project (n = 197)
SNP | $A F (%(n)) | $A F (%(n)) | $A F (%(n)) | $A F (%(n)) | ||||
|---|---|---|---|---|---|---|---|---|
| Â | del | non-del | non-del | control | del | control | control | #1000GPD |
rs5748417 | Â | Â | Â | Â | Â | Â | Â | Â |
T | 53.8(7) | 68.6(273) | 68.6(273) | 59.0(164) | 53.8(7) | 59.0(164) | 59.0(164) | 66.0(260) |
C | 46.2(6) | 31.4(125) | 31.4(125) | 41.0(114) | 46.2(6) | 41.0(114) | 41.0(114) | 34.0(134) |
χ 2 | 1.261 | 6.600 | 0.136 | 3.427 | ||||
*P(df = 1) | 0.363 | 0.011 | 0.777 | 0.074 | ||||
rs5748418 | Â | Â | Â | Â | Â | Â | Â | Â |
G | 53.8(7) | 72.9(290) | 72.9(290) | 59.0(164) | 53.8(7) | 59.0(164) | 59.0(164) | 66.0(260) |
A | 46.2(6) | 27.1(108) | 27.1(108) | 41.0(114) | 46.2(6) | 41.0(114) | 41.0(114) | 34.0(134) |
χ 2 | 2.272 | 14.28 | 0.136 | 3.427 | ||||
*P(df = 1) | 0.203 | 2.0E-4 | 0.777 | 0.074 | ||||
rs737868 | Â | Â | Â | Â | Â | Â | Â | Â |
G | 46.2(6) | 31.7(126) | 31.7(126) | 38.8(108) | 46.2(6) | 38.8(108) | 38.8(108) | 39.8(157) |
C | 53.8(7) | 68.3(272) | 68.3(272) | 61.2(170) | 53.8(7) | 61.2(170) | 61.2(170) | 60.2(237) |
χ 2 | 1.213 | 3.739 | 0.278 | 0.068 | ||||
*P(df = 1) | 0.364 | 0.059 | 0.772 | 0.081 | ||||
rs41298814 | Â | Â | Â | Â | Â | Â | Â | Â |
T | 61.5(8) | 46.2(184) | 46.2(184) | 51.8(144) | 61.5(8) | 51.8(144) | 51.8(144) | 51.5(203) |
C | 38.5(5) | 53.8(214) | 53.8(214) | 48.2(134) | 38.5(5) | 48.2(134) | 48.2(134) | 48.5(191) |
χ 2 | 1.185 | 2.031 | 0.472 | 0.005 | ||||
*P(df = 1) | 0.398 | 0.160 | 0.577 | 1.000 | ||||
rs2301558 | Â | Â | Â | Â | Â | Â | Â | Â |
T | 23.1(3) | 14.8(59) | 14.8(59) | 14.4(40) | 23.1(3) | 14.4(40) | 14.4(40) | 12.4(49) |
C | 76.9(10) | 85.2(339) | 85.2(339) | 85.6(238) | 76.9(10) | 85.6(238) | 85.6(238) | 87.6(345) |
χ 2 | 0.669 | 0.025 | 0.744 | 0.540 | ||||
*P(df = 1) | 0.426 | 0.912 | 0.744 | 0.489 | ||||
rs41298840 | Â | Â | Â | Â | Â | Â | Â | Â |
A | 76.9(10) | 44.7(178) | 44.7(178) | 47.1(131) | 76.9(10) | 47.1(131) | 47.1(131) | 52.3(206) |
G | 23.1(3) | 55.3(220) | 55.3(220) | 52.9(147) | 23.1(3) | 52.9(147) | 52.9(147) | 47.7(188) |
χ 2 | 5.275 | 0.379 | 4.416 | 1.737 | ||||
*P(df = 1) | 0.025 | 0.583 | 0.046 | 0.210 | ||||
rs4819522 | Â | Â | Â | Â | Â | Â | Â | Â |
C | 76.9(10) | 86.3(344) | 86.4(344) | 86.3(240) | 76.9(10) | 86.3(240) | 86.3(240) | 87.1(343) |
T | 23.1(3) | 13.6(54) | 13.6(54) | 13.7(38) | 23.1(3) | 13.7(38) | 13.7(38) | 12.9(51) |
χ 2 | 0.953 | 0.001 | 0.908 | 0.075 | ||||
*P(df = 1) | 0.403 | 1.000 | 0.404 | 0.818 | ||||
rs5746826 | Â | Â | Â | Â | Â | Â | Â | Â |
G | 53.8(7) | 33.9(135) | 33.9(135) | 38.1(106) | 53.8(7) | 38.1(106) | 38.1(106) | 37.6(148) |
T | 46.2(6) | 66.1(263) | 66.1(263) | 61.9(172) | 46.2(6) | 61.9(172) | 61.9(172) | 62.4(246) |
χ 2 | 2.211 | 1.264 | 1.292 | 0.022 | ||||
*P(df = 1) | 0.148 | 0.289 | 0.262 | 0.936 | ||||