Table 4 Groupwise association testing of ZNF750 functional groups with psoriasis
From: Association analysis identifies ZNF750 regulatory variants in psoriasis
Rare Variant Group | Total Variants, Cases (n = 716) | Total Variants, Controls (n = 397) | P-value, Weighted Sum Statistic |
|---|---|---|---|
5' Regulatory (Promoter + 5' UTR) | 10 | 1 | 0.041 |
All Coding | 30 | 19 | 0.575 |
   - Non-synonymous | 25 | 15 | 0.560 |
   - Predicted deleterious | 24 | 11 | 0.314 |
3' UTR | 5 | 2 | 0.351 |
All Rare | 67 | 32 | 0.192 |