Table 3 Genotype association between BMP4.1 and BMP4.2 polymorphisms and NSCLP.
From: Risk variants in BMP4 promoters for nonsyndromic cleft lip/palate in a Chilean population
Promoter | Polymorphism | Genotypes | Frequency | Odds Ratio (95% C.I.) | p-value | |
|---|---|---|---|---|---|---|
Cases | Controls | |||||
rs2855527 | T/T | 0.9938 | 0.9941 | Ref. | ||
BMP4.1 | T/G | 0.0062 | 0.0059 | 1.04 (0.09-11.6) | 0.972 | |
rs77671695 | T/T | 0.92 | 0.89 | Ref. | ||
T/G | 0.08 | 0.11 | 0.71 (0.36-1.37) | 0.308 | ||
delAACCCGGG | Ins/Ins | 0.92 | 0.88 | Ref. | ||
Ins/Del | 0.08 | 0.12 | 0.63 (0.32-1.25) | 0.189 | ||
G/G | 0.14 | 0.15 | Ref. | |||
rs2855530 | C/G | 0.56 | 0.44 | 1.75 (1.14-2.69) | 0.012 | |
C/C | 0.30 | 0.41 | 0.79 (0.43-1.47) | 0.020 | ||
BMP4.2 | rs113141288 | G/G | 0.92 | 0.90 | Ref. | |
G/T | 0.08 | 0.10 | 0.77 (0.39-1.50) | 0.443 | ||
rs76953585 | C/C | 0.92 | 0.89 | Ref. | ||
C/T | 0.08 | 0.11 | 0.78 (0.41-1.51) | 0.472 | ||
rs113562279 | G/G | 0.92 | 0.89 | Ref. | ||
G/T | 0.08 | 0.11 | 0.69 (0.34-1.36) | 0.282 | ||