Table 2 Allelic association between BMP4.1 and BMP4.2 polymorphisms and NSCLP subdivided by gender.
From: Risk variants in BMP4 promoters for nonsyndromic cleft lip/palate in a Chilean population
Promoter | Polymorphism | Males MAFa | Odds Ratio (95% C.I.) | p-value | Females MAF# | Odds Ratio (95% C.I.) | p-value | ||
|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | ||||||
BMP4.1 | rs2855527 | 0.0047 | 0.0027 | 1.74 (0.11-27.95) | 0.692 | 0.000 | 0.0033 | --- | --- |
rs77671695 | 0.042 | 0.057 | 0.73 (0.33-1.63) | 0.444 | 0.035 | 0.052 | 0.65 (0.21-2.00) | 0.454 | |
delAACCCGGG | 0.029 | 0.060 | 0.47 (0.19-1.17) | 0.099 | 0.059 | 0.058 | 1.01 (0.39-2.64) | 0.982 | |
rs2855530 | 0.456 | 0.356 | 1.52 (1.07-2.15) | 0.019 | 0.327 | 0.384 | 0.78 (0.48-1.25) | 0.297 | |
BMP4.2 | rs113141288 | 0.043 | 0.051 | 0.84 (0.37-1.92) | 0.685 | 0.036 | 0.054 | 0.66 (0.21-2.00) | 0.456 |
rs76953585 | 0.042 | 0.058 | 0.71 (0.32-1.59) | 0.405 | 0.045 | 0.050 | 0.91 (0.32-2.57) | 0.860 | |
rs113562279 | 0.037 | 0.058 | 0.63 (0.27-1.45) | 0.273 | 0.037 | 0.046 | 0.78 (0.25-2.41) | 0.295 | |