Figure 1From: Antagonistic pleiotropy as a widespread mechanism for the maintenance of polymorphic disease alleles Expected equilibrium frequency of the disease phenotype caused by an overdominant antagonistically pleiotropic allele. Equilibrium frequencies for heterozygous advantages, Sadv, of 0.1%, 1%, 5% and 25% are shown for a range of homozygous deleterious effects, Sdel, ranging from 0% (no deleterious effect) to 100% (allele is lethal or homozygotes are always sterile). Note the Log10 scale on the Y-axis.Back to article page