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Table 3 Summary of different comparative results

From: The insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme gene and cancer risk: a meta-analysis

Variables

N

Cases/Controls

DD+DI vs II

DD vs DI+II

DD vs II

D vs I

DI vs II

   

OR(95%CI)

P*

OR(95%CI)

P*

OR(95%CI)

P*

OR(95%CI)

P*

OR(95%CI)

P*

Total

25

3914/11391

0.88(0.73, 1.06)

0.38

0.93(0.80, 1.09)

0.39

0.90(0.73, 1.12)

0.34

0.94(0.83, 1.07)

0.34

0.89(0.75, 1.06)

0.20

Subgroup by ethnicity

           

Asian

8

1201/1950

1.13(0.96, 1.33)

0.15

1.05(0.74, 1.49)

0.78

1.09(0.83, 1.44)

0.53

1.08(0.93, 1.25)

0.34

0.85(0.68, 1.06)

0.14

European

14

2188/8130

0.89(0.73, 1.09)

0.26

0.89(0.73, 1.09)

0.26

0.76(0.53, 1.08)

0.12

0.86(0.71, 1.03)

0.10

0.78(0.60, 1.01)

0.06

Subgroup by cancer type

           

Lung

7

737/6511

1.04(0.70, 1.55)

0.85

0.99(0.67, 1.48)

0.98

1.02(0.62, 1.69)

0.93

1.03(0.80, 1.31)

0.83

1.01(0.64, 1.61)

0.95

Breast

5

1235/8057

0.88(0.71, 1.09)

0.24

0.95(0.75, 1.21)

0.70

0.86(0.64, 1.16)

0.33

0.94(0.81, 1.09)

0.41

0.88(0.72, 1.09)

0.24

Colorectal

4

517/6456

0.81(0.53, 1.24)

0.34

0.83(0.66, 1.05)

0.11

0.73(0.45, 1.18)

0.20

0.87(0.71, 1.06)

0.17

0.87(0.58, 1.31)

0.50

Gastric

3

434/775

1.06(0.71, 1.59)

0.78

0.94(0.66, 1.36)

0.76

0.96(0.55, 1.65)

0.87

1.00(0.74, 1.34)

1.00

1.12(0.79, 1.58)

0.52

Prostate

3

276/6094

2.44(0.66, 8.97)

0.18

2.05(0.74, 5.62)

0.17

3.48(0.63, 19.13)

0.15

2.05(0.84, 5.02)

0.11

1.66(0.67, 4.07)

0.27

  1. *: P value for Q-test.