Table 5 Distribution of SERPINE2 haplotypes according to the existence and severity of panlobular emphysematous changes
From: SERPINE2 haplotype as a risk factor for panlobular type of emphysema
Haplotype# | No radiologic changes* N (%)¶ | Radiologic changes+ N (%)¶ | OR (95% CI) ++ | Subnormal changes± N (%)¶ | OR (95% CI) ++ | Pathological changes§ N (%)¶ | OR (95% CI) ++ |
|---|---|---|---|---|---|---|---|
GCψ | 834 (53.3) | 165 (49.1) | 1.0 | 117 (53.7) | 1.0 | 48 (40.7) | 1.0 |
GT | 429 (27.4) | 79 (23.5) | 0.92 (0.68-1.24) | 49 (22.5) | 0.80 (0.56-1.14) | 30 (25.4) | 1.20 (0.74-1.94) |
CC | 289 (18.5) | 83 (24.7) | 1.41 (1.04-1.92) | 45 (20.6) | 1.09 (0.75-1.59) | 38 (32.2) | 2.23 (1.41-3.54) |
CT | 14 (0.9) | 9 (2.7) | 3.72 (1.56-8.90) | 7 (3.2) | 3.98 (1.55-10.20) | 2 (1.7) | 2.71 (0.58-12.59) |