|
Trait
|
N
|
p (ADD Mode)
|
beta (ADD)
|
SE beta
|
|---|
|
total cholesterol [mmol/l]
|
907
|
0.17
|
0.011
|
0.008
|
|
HDL cholesterol [mmol/l]
|
907
|
0.78
|
0.003
|
0.010
|
|
LDL cholesterol [mmol/l]
|
907
|
0.10
|
0.021
|
0.013
|
|
Triglycerides [mmol/l]
|
907
|
0.41
|
0.018
|
0.022
|
|
Apolipoprotein-B [g/l]
|
905
|
0.17
|
0.015
|
0.011
|
|
fasting insulin [pmol/l]
|
886
|
0.42
|
-0.020
|
0.025
|
|
fasting glucose [mmol/l]
|
886
|
0.46
|
0.003
|
0.004
|
|
BMI [kg/m2]
|
1019
|
0.23
|
-0.009
|
0.007
|
|
fat mass [%]
|
1019
|
0.91
|
0.002
|
0.017
|
- Association of rs9514089 with components of the metabolic syndrome. Analyses were performed in the additive (ADD) mode of inheritance by linear regression analyses. Age, gender and BMI were used as covariates (for BMI and fat mass only age and gender). Results are presented as betas and their standard errors (SE). Effect directions were standardized to the minor allele. For analyses of glucose and insulin only non-diabetic subjects were included, effects on lipid traits were only assessed in subjects without lipid-lowering medication.
