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Table 2 Multivariable Cox-regression analysis of BRCA1 c.4034delA and c.5266dupC mutation carriers breast cancer patients

From: Genotype-phenotype correlations among BRCA14153delA and 5382insC mutation carriers from Latvia

Variable

n

HR

95%CI

P-value

BRCA1 mutations:

    

   c.4034delA

25

2.76

1.13 - 6.70

0.02

   c.5266dupC

68

   

Tumor size:

    

   < 5 cm

74

0.36

0.15 - 0.86

0.02

   > 5 cm

19

   

Axillary node:

    

   Negative

44

0.34

0.13 - 0.89

0.03

   Positive

49

   

Age at diagnosis:

    

   < 50

51

1.53

0.65 - 3.61

0.32

   > 50

42

   
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BMC Medical Genetics

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