Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk

Table 5 Results of Linear Model analysis using 4 algorithms to estimate heritability V(g)/Vp

	AI Algorithm		Fisher Algorithm		EM Algorithm		HE Regression Algorithm
Source	Variance	SE	Variance	SE	Variance	SE	Variance	SE	P-value
V(g)	0.000668	0.000569	0.000668	0.000551	0.000727	0.000552	0.250341	0.133737
Vp	0.002151	0.000087	0.002151	0.000086	0.002152	0.000087	1.354157	0.015038
V(g)/Vp	0.310483	0.263126	0.310483	0.254964	0.337865	0.25492	0.184869	0.098453	0.026*
logL	3222.103		3222.103		3222.098
n	1270		1270		1270		6725

Algorithm type and their respective heritability estimates and standard errors are highlighted.

ISSN: 1471-2350