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Table 5 Association between IL13 polymorphisms and rhinoconjunctivitis, stratified by smoking status in Japanese women, KOMCHS, Japan

From: Case-control study of IL13 polymorphisms, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study

  

Smoking status

 
  

No

Yes

 

SNP

Genotype

No. cases/controls

Adjusted OR (95% CI)*

No. cases/controls

Adjusted OR (95% CI)*

P for interaction

rs1800925

      

   Model 1

CC

185/370

1.00

85/146

1.00

 
 

CT

75/156

1.08 (0.76 - 1.52)

35/74

0.76 (0.46 - 1.25)

0.30

 

TT

8/17

0.75 (0.30 - 1.87)

5/4

2.48 (0.63 - 9.74)

0.17

   Model 2

CC

185/370

1.00

85/146

1.00

 
 

CT + TT

83/173

1.04 (0.74 - 1.45)

40/78

0.84 (0.52 - 1.35)

0.53

rs20541

      

   Model 1

GG

129/275

1.00

56/104

1.00

 
 

GA

113/227

1.16 (0.84 - 1.60)

52/106

0.82 (0.50 - 1.34)

0.28

 

AA

26/40

1.46 (0.83 - 2.56)

17/14

2.10 (0.94 - 4.67)

0.37

   Model 2

GG

129/275

1.00

56/104

1.00

 
 

GA + AA

139/267

1.20 (0.88 - 1.64)

69/120

0.98 (0.62 - 1.55)

0.52

  1. * Adjusted for age, region of residence, presence of older siblings, family history of allergic rhinitis, and education.
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BMC Medical Genetics

ISSN: 1471-2350

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