Skip to main content

Table 2 Characteristics of type 1 diabetes patients according to the Glomerular Filtration Rate (GFR) status.

From: Association of genetic variants in the promoter region of genes encoding p22phox (CYBA) and glutamate cysteine ligase catalytic subunit (GCLC) and renal disease in patients with type 1 diabetes mellitus

 

GFR ≥ 60 mL/min/1.73 m2 (n = 265)

GFR < 60 mL/min/1.73 m2

(n = 136)

pvalue

Sex (male/female) (%)

42/58

50/50

0.1410

Age (years)

33 (25.7-42.8)

38 (30.8-45.6)

0.003

Age at diabetes diagnosis (years)

11.5 (6-18)

13 (9-20.7)

0.1206

Duration of diabetes (years)

20.6 (16.1-25.1)

23 (18-31)

0.0086

Arterial hypertension (%)

36.7

64.5

< 0.0001

Use of lipid-lowering drugs (%)

16.4

25.3

0.0325

Use of ACE inhibitors (%)

21.7

21

0.8591

HbA1C (%)

8.25 (7.4-9.7)

8.4 (7.4-9.8)

0.7027

Cholesterol (mg/dL)

172 (149-199)

179 (151-211)

0.1437

HDL cholesterol (mg/dL)

58 (49-69)

52 (43-64.2)

0.0134

LDL cholesterol (mg/dL)

91 (76-113)

103 (78-129)

0.0634

Triglycerides (mg/dL)

71 (53-107)

98 (72-145)

< 0.0001

  1. Data are median ± interquartile interval; ACE: angiotensin converting enzyme; GFR: glomerular filtration rate.