Effect of heme oxygenase-1 polymorphisms on lung function and gene expression

Table 2 Single nucleotide polymorphisms (SNPs) in the HMOX1 region genotyped in this study

		MAF in the rate of decline study			MAF in the baseline study
SNP	Alleles (major/minor)	Fast decline	Non decline	P value*	Low function	High function	P value*
rs9610289	G/A	0.301	0.311	0.689	0.342	0.342	0.894
rs2071746	A/T	0.405	0.434	0.223	0.429	0.436	0.931
rs2071747	G/C	0.058	0.065	0.163	0.050	0.046	0.656
rs2071749	G/A	0.495	0.452	0.015	0.475	0.458	0.184
rs2285112	A/G	0.356	0.370	0.572	0.397	0.395	0.933

MAF = minor allele frequency
* P values in the table are for the codominant model and are adjusted by multivariate logistic regression for age, sex, pack-years of smoking, and research center.