Table 2 Effect of KCNE1 D85N on age-, sex-, and heart rate-adjusted QT interval
From: KCNE1D85N polymorphism — a sex-specific modifier in type 1 long QT syndrome?
Total n | n with D85N | Effect (ms) | SE (ms) | pvalue | |
|---|---|---|---|---|---|
All founder mutation carriers | 712 | 23 | +13.1 | 6.0 | 0.028 |
Malesa | 290 | 10 | +20.1 | 7.7 | 0.010 |
Femalesa | 422 | 13 | +1.6 | 9.1 | 0.857 |
KCNQ1 G589D carriers | 492 | 18 | +16.9 | 6.3 | 0.007 |
Malesa | 213 | 8 | +25.7 | 8.6 | 0.003 |
Femalesa | 279 | 10 | +0.7 | 9.2 | 0.935 |