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Table 1 Characteristics of the genotyped subjects from the Ashkenazi Jewish, NINDS, and CIDR/Pankratz et al 2009 datasets

From: Genome-Wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population

 

Ashkenazi Jews

NINDS

CIDR/Pankratz et al 2009

Overall

 

Case

Control

Case

Control

Case

Control

Case

Control

Subjects (%)

268(60.1)

178(39.9)

923(53.6)

798(46.4)

859(50.0)

860(50.0)

2050(52.8)

1836(47.2)

Mean age at onset/examination Year ± SD*

59.9 ± 12.1

69.8 ± 8.8

58.5 ± 13.2

58.6 ± 16.4

61.8 ± 10.9

54.8 ± 13.0

60.0 ± 12.2

57.9 ± 14.9

Male(%)

255(57.2)

886(51.5)

850(49.4)

1991(51.2)

Proportion of EOPD#

24.5%

26.0%

15.0%

21.3%

Total

446

1721

1719

3886

Genotyping rate

99.85

99.79

99.81

99.82

Markers passing QC

525124

517805

334161

 
  1. * Age at onset for cases and age at examination for controls, # EOPD: Early Onset of PD, with age at onset younger than or equal to 50