|
Ashkenazi Jews
|
NINDS
|
CIDR/Pankratz et al 2009
|
Overall
|
---|
|
Case
|
Control
|
Case
|
Control
|
Case
|
Control
|
Case
|
Control
|
---|
Subjects (%)
|
268(60.1)
|
178(39.9)
|
923(53.6)
|
798(46.4)
|
859(50.0)
|
860(50.0)
|
2050(52.8)
|
1836(47.2)
|
Mean age at onset/examination Year ± SD*
|
59.9 ± 12.1
|
69.8 ± 8.8
|
58.5 ± 13.2
|
58.6 ± 16.4
|
61.8 ± 10.9
|
54.8 ± 13.0
|
60.0 ± 12.2
|
57.9 ± 14.9
|
Male(%)
|
255(57.2)
|
886(51.5)
|
850(49.4)
|
1991(51.2)
|
Proportion of EOPD#
|
24.5%
|
26.0%
|
15.0%
|
21.3%
|
Total
|
446
|
1721
|
1719
|
3886
|
Genotyping rate
|
99.85
|
99.79
|
99.81
|
99.82
|
Markers passing QC
|
525124
|
517805
|
334161
| |
- * Age at onset for cases and age at examination for controls, # EOPD: Early Onset of PD, with age at onset younger than or equal to 50