Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population

BMC Medical Genetics

Table 2 Meta-analysis of rs7903146 in TCF7L2 with T2D in the Han Chinese populations

			Genotyping count								Allele frequency		Multiplicative model
Authors	Samples collected	References	Cases				Controls				Risk allele (T)
			Total N	CC	CT	TT	Total N	CC	CT	TT	Case	Control	p value	OR (95% CI)^b
Ren et al	Beijing (North China)	24	481	438	41	2	491	463	26	2	0.047	0.03	0.063	1.93 (1.13-3.49)
Ng et al	Hong Kong (South China)	27	433	408	24	1	419	399	20	0	0.031	0.024	0.17	1.29 (0.90-1.87)
Chang et al	Taiwan (East China)	25	760	724	35	1	760	716	44	0	0.024	0.029	0.36	0.81 (0.50-1.31)
Lin et al	Chengdu (West China)	This study	1529	1348	178	3	1439	1328	107	4	0.060	0.040	0.00038	1.54 (1.21-1.95)
Combined all	Han Chinese in China		3203	2918	278	7	3109	2906	197	6	0.046	0.034	0.00058	1.37 (1.15-1.65)
N, Number; b, OR, odds ratio, CI, confidence interval

ISSN: 1471-2350