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Table 2 Quantitative association results for the candidate loci in the European American height cohort (n = 8,184), sorted by chromosomal location.

From: The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature

Chr

Minor Allele

SNP

Position (Build 36)

Nearby genes(s)

NMISS

MAF

BETA

SE

R2

T

P

1

A

rs11809207

26205282

CATSPER4

8106

0.1730

0.02775

0.0213

0.0002095

1.303

0.1926

1

C

rs6663565

41232781

SCMH1

8184

0.4297

0.03744

0.01587

0.0006802

2.36

0.0183

1

C

rs17038164

118574711

SPAG17

8182

0.2601

-0.06029

0.01784

0.001395

-3.38

0.0007274

1

G

rs11205277

146705945

Histone class 2A, MTMR11, SV2A, SF3B4

8182

0.4195

0.0109

0.01579

5.83E-05

0.6906

0.4898

1

G

rs678962

168921546

DNM3

8178

0.2183

0.01272

0.0192

5.37E-05

0.6625

0.5077

1

A

rs2274432

180752602

C1orf19, GLT25D2

7965

0.3237

0.04568

0.01722

0.0008828

2.653

0.008003

1

A

rs3942992

224079131

ZNF678

8181

0.1725

9.96E-05

0.02072

2.83E-09

0.004809

0.9962

2

G

rs3791679

56008543

EFEMP1, PNPT1

8179

0.2539

-0.0782

0.01798

0.002308

-4.349

1.39×10 -5

2

T

rs1052483

219759853

IHH, CRYBA2, FEV, SLC23A3, TUBA1

8110

0.0956

-0.04701

0.02686

0.0003777

-1.75

0.08009

3

C

rs9841212

135674636

ANAPC13, CEP63

8154

0.3289

-0.006868

0.01676

2.06E-05

-0.4098

0.682

3

A

rs6763931

142585531

ZBTB38

8174

0.4091

0.04634

0.01587

0.001042

2.92

0.003513

4

T

rs6842303

17530324

LCORL, NCAPG

8173

0.2466

0.02231

0.01823

0.0001834

1.224

0.2209

4

C

rs6830062

17693999

LCORL, NCAPG

8184

0.1883

-0.05215

0.02014

0.0008192

-2.59

0.009613

4

A

rs1812175

145932449

HHIP

8172

0.1639

-0.03329

0.02125

0.0003002

-1.566

0.1173

5

T

rs10472828

32924575

NPR3

8182

0.4585

-0.005366

0.01589

1.39E-05

-0.3376

0.7357

6

A

rs12198986

7665058

BMP6

8183

0.4516

-0.0003072

0.01598

4.52E-08

-0.01922

0.9847

6

G

rs10946808

26341366

Histone class 1, Butyrophilin genes

8164

0.2923

-0.05734

0.01736

0.001336

-3.304

0.0009572

6

C

rs2844479

31680935

HLA class III

8183

0.3890

-0.03031

0.01605

0.0004355

-1.888

0.05907

6

G

rs3130050

31726740

HLA class III

8178

0.1249

0.06717

0.02369

0.0009819

2.835

0.004598

6

T

rs185819

32158045

HLA class III

8178

0.4576

0.0516

0.01576

0.001309

3.274

0.001066

6

G

rs1776897

34302989

HMGA1, LBH

8183

0.0940

0.02524

0.02701

0.0001068

0.9348

0.3499

6

A

rs2814993

34726871

C6orf106

8091

0.1390

0.06941

0.02284

0.001141

3.039

0.002378

6

A

rs4713858

35510763

ANKS1, TCP11, ZNF76, DEF6, SCUBE3

8184

0.1730

-0.02058

0.02103

0.000117

-0.9786

0.3278

6

C

rs314263

105499438

LIN28B, HACE1, BVES, POPDC3

8184

0.3129

0.02821

0.01698

0.0003373

1.661

0.09665

6

T

rs1490388

126877348

C6orf173/LOC387103

8179

0.4784

0.05315

0.01571

0.001398

3.383

0.0007196

6

G

rs3748069

142809326

GPR126

8184

0.3126

-0.06047

0.01695

0.001552

-3.566

0.0003641

7

T

rs798544

2536343

GNA12

8184

0.2897

0.009501

0.01746

3.62E-05

0.5441

0.5864

7

C

rs1182188

2643226

GNA12

8184

0.2948

0.01528

0.01742

9.40E-05

0.8769

0.3806

7

A

rs849141

27958331

JAZF1

8180

0.2729

0.05199

0.01769

0.001055

2.939

0.0033

7

C

rs2282978

91909061

CDK6, PEX1, GATAD1, ERVWE1

8180

0.3562

-0.0002285

0.01639

2.38E-08

-0.01394

0.9889

7

C

rs11765954

91925346

CDK6, PEX1, GATAD1, ERVWE1

8183

0.2866

0.006002

0.01744

1.45E-05

0.3441

0.7307

8

C

rs10958476

57258362

PLAG1, MOS, CHCHD7, RDHE2, RPS20, LYN, TGS1, PENK

8158

0.2015

0.05689

0.01979

0.001012

2.874

0.004062

8

C

rs7846385

78322734

PXMP3, ZFHX4

8175

0.2753

0.004128

0.01761

6.72E-06

0.2344

0.8147

9

G

rs4448343

95345925

PTCH1

8182

0.3217

-0.007508

0.01686

2.42E-05

-0.4453

0.6561

9

A

rs4743034

106711908

ZNF462

8183

0.2250

0.01859

0.01872

0.0001206

0.9933

0.3206

12

C

rs8756

64646019

HMGA2

8175

0.4607

0.02308

0.01586

0.0002588

1.455

0.1458

12

G

rs3825199

92479422

SOCS2, MRPL42, CRADD, UBE2N

8183

0.2088

0.02109

0.0194

0.0001445

1.087

0.2769

13

C

rs1239947

50004556

DLEU7

8183

0.3287

0.03243

0.01678

0.0004563

1.933

0.05333

14

C

rs910316

74695795

TMED10

8184

0.4863

-0.02021

0.01577

0.0002006

-1.281

0.2002

14

C

rs7153027

91496975

TRIP11, FBLN5, ATXN3, CPSF2

8149

0.4316

-0.02966

0.0158

0.0004323

-1.877

0.06054

15

C

rs2554380

82106888

ADAMTSL3, SH3GL3

8067

0.1991

0.01455

0.02029

6.38E-05

0.7171

0.4734

15

T

rs11633371

87157836

ACAN

8184

0.4636

0.02862

0.01575

0.0004032

1.817

0.06929

15

A

rs4533267

98603794

ADAMTS17

8184

0.2933

-0.001093

0.01737

4.84E-07

-0.06294

0.9498

17

A

rs3760318

26271841

CRLF3, ATAD5, CENTA2, RNF135

8184

0.3821

-0.03009

0.01627

0.0004178

-1.849

0.06444

17

A

rs4794665

52205328

NOG, DGKE, TRIM25, COIL, RISK

8183

0.4756

0.006489

0.01569

2.09E-05

0.4135

0.6792

17

A

rs757608

56852059

BCAS3, NACA2, TBX2, TBX4

8126

0.3322

0.02008

0.01676

0.0001767

1.198

0.2309

18

G

rs4800148

18978326

CABLES1, RBBP8, C18orf45

8183

0.2043

-0.04987

0.01943

0.0008048

-2.567

0.01028

18

T

rs530550

45105636

DYM

8182

0.3572

-0.01124

0.01631

5.81E-05

-0.6892

0.4907

19

G

rs12459350

2127586

DOT1L

8179

0.4744

0.02751

0.01579

0.0003711

1.742

0.08149

20

A

rs967417

6568893

BMP2

8184

0.4495

-0.02479

0.01591

0.0002964

-1.558

0.1194

20

C

rs4911494

33435328

UQCC, GDF5, CEP250, EIF6, MMP24

8182

0.3864

0.05107

0.01621

0.001212

3.151

0.001633

  1. The SNPs in bold are those that survived correction for multiple testing.
  2. NMISS: number of individuals tested; MAF: minor allele frequency; BETA: regression coefficient for the test SNP; SE: standard error of the regression coefficient; R2: r2 value in linear regression; T: test statistic; P: two-sided trend test P-value. The direction of effect is shown for the minor allele in each case.