Table 1 Demographic characteristics of study subjects

Age(yr)

38.1 ± 6.7 (15-45) †

26.0 ± 8.1 (16-45)

52.6 ± 12.2 (17-87)

Male

124(65.3%)†

336(45.2%)

482(47.6%)

Diabetes

65(34.2%) †

8(1.1%)

103(10.2%)

Hypertension

76(42.5%)†

45(6.1%)

318(31.4%)

Hyperlipidemia

18(10.8%)†

22(3.1%)

53(5.4%)

Smoker (current + past vs. never)

89(48.1%)†

60(8.1%)

208(20.7%)

Total cholesterol (mmol/L)

4.77 ± 1.30†

4.36 ± 0.89

4.83 ± 0.87

PDE4D rs702553

AA

60(32.6%)

278(37.9%)

352(36.3%)

AT

80(43.5%)

339(46.2%)

451(46.4%)

TT

44(23.9%) *

117(15.9%)

168(17.3%)