Figure 1
From: Low penetrance of a SDHB mutation in a large Dutch paraganglioma family
Pedigree with clinical data. The arrow shows the index patient. The non-carriers have been collapsed to minimize recognition of the pedigree.+, mutation present; -, mutation absent; C, clinical screening; N, no symptoms (but not screened); RC, rectal carcinoma; Ov, ovarian carcinoma; EC, endometrial carcinoma; BC, breast cancer (tumors with age at diagnosis in years).