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Table 2 Clinical characteristics of patients

From: The CTLA4 variants may interact with the IL23R- and NOD2-conferred risk in development of Crohn's disease

 

Total

(n = 333)

Pediatric-onset CD

(n = 137)

Adult-onset CD

(n = 196)

Age at diagnosis

   

   A1 (<17 years)

111

111

0

   A2 (17 - 40 years)

190

26

164

   A3 (>40 years)

32

0

32

Localization

   

   L1 (terminal ileum)

71 (21%)

23 (17%)

48 (25%)

   L2 (colon)

50 (15%)

13 (9.5%)

37 (19%)

   L3 (ileocolon)

208 (63%)

101 (74%)

107 (55%)

   L 1-3 not determined

4

0

4

   L4 (Upper GI)1

56 (17%)

20 (15%)

36 (18%)

Disease behavior

   

   B1 (nonstricturing/nonpenetraiting)

138 (42%)

79 (59%)

59 (30%)

   B2 (stricturing)

129 (39%)

34 (25%)

95 (49%)

   B3 (penetrating)

62 (18%)

21 (16%)

41 (21%)

   B 1-3 not determined

4

3

1

   B4 (perianal disease)

109 (33%)

32 (23%)

77 (39%)

Extraintestinal manifestation2

53 (16%)

21 (15%)

32 (17%)

Need for surgery3

173 (52%)

41 (30%)

132 (68%)

  1. 1: GI: gastrointestinal.
  2. 2: Either of: peripheral arthritis, ankylosing spondylitis, sacroilitis, episcleritis and iritis, erythema nodosum, pyoderma gangrenosum, or sclerosing cholangitis.
  3. 3: Abdominal surgery for complication of CD (resection)