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Table 4 Diplotype frequencies in the promoter region and the 3' UTR of GRP78 gene in HBV carriers and controls, and risk of HBV

From: Lack of association between the GRP78 polymorphisms in the promoter and 3' UTR and susceptibility to chronic HBV infection in a Chinese Han population

Diplotypes

Cases (%)

Controls (%)

OR (95% CI)

p

Promoter

    

GCTd/GCTd

130 (25.77)

156 (28.86)

1

 

ACCG/GCTd

123 (24.86)

128 (23.84)

1.20 (0.83-1.76)

0.196

GCTd/GTCd

75 (15.14)

81 (14.90)

1.11 (0.74-1.65)

0.153

ACCG/GTCd

55 (11.17)

49 (9.12)

1.57 (0.97-2.55)

0.462

GCCd/GCTd

38 (7.75)

40 (7.45)

1.19 (0.72-2.07)

0.259

ACCG/GCCd

20 (3.96)

23 (4.28)

1.04 (0.53-2.00)

0.754

GTCd/GTCd

18 (3.42)

22 (4.10)

0.89 (0.45-1.75)

0.410

GCCd/GTCd

14 (2.88)

21 (3.91)

0.84 (0.41-1.72)

0.388

ACCG/ACCG

23 (5.05)

19 (3.54)

1.66 (0.85-3.24)

0.071

p-trenda

  

0.142

 

3' UTR

    

TCC/TTT

203 (41.62)

214 (39.66)

1

 

TTT/TTT

129 (25.41)

168 (31.10)

1.30 (0.95-1.80)

0.249

TCC/TCC

108 (21.80)

98 (18.25)

1.50 (0.75-2.28)

0.166

CCT/TTT

33 (6.67)

32 (5.96)

1.43 (0.82-2.46)

0.215

CCT/TCC

19 (3.78)

23 (4.28)

0.97 (0.55-2.13)

0.647

CCT/CCT

4 (0.72)

4 (0.74)

1.36 (0.26-6.08)

0.076

p-trenda

  

0.091

 
  1. Note: OR, odds ratio; d, delete base.
  2. aTest for trend of odds was two sided and was based on likelihood ratio tests assuming a multiplicative model for all cases.