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Table 3 Haplotype frequencies in the promoter region and the 3' UTR of GRP78 gene in HBV carriers and controls, and risk of HBV

From: Lack of association between the GRP78 polymorphisms in the promoter and 3' UTR and susceptibility to chronic HBV infection in a Chinese Han population

Haplotypes

Cases (%)

Controls (%)

OR (95% CI)

P

Promoter

    

G-C-T-d

496 (49.64)

561 (51.96)

1

 

A-C-C-G

244 (25.04)

238 (22.16)

1.26 (0.92-1.58)

0.107

G-T-C-d

180 (18.02)

195 (18.08)

1.05 (0.80-1.35)

0.376

G-C-C-d

72 (7.30)

84 (7.82)

0.95 (0.71-1.32)

0.552

p-trenda

  

0.247

 

3' UTR

    

T-T-T

494 (49.55)

582 (53.91)

1

 

T-C-C

438 (44.50)

433 (40.22)

1.15 (0.87-1.46)

0.269

C-C-T

60 (5.95)

63 (5.87)

1.21 (0.76-1.65)

0.122

p-trenda

  

0.181

 
  1. Note: OR, odds ratio, d, delete base.
  2. aTest for trend of odds was two sided and was based on likelihood ratio tests assuming a multiplicative model for all cases.
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BMC Medical Genetics

ISSN: 1471-2350

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