The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

Table 3 Genotypes in Danish patients with ulcerative colitis¹.

	N_case	N_control	OR (95%CI)²		OR (95%CI)³		OR (95%CI)⁴		P-value⁵
IL1 β C-31T (rs1143627)
TT	204	342	1.00	-	1.00	-	1.00	-
CT	238	342	1.17	(0.92-1.48)	1.15	(0.90-1.47)	1.15	(0.89-1.47)	0.28
CC	56	95	0.99	(0.68-1.43)	0.99	(0.68-1.46)	1.02	(0.69-1.49)	0.94
CT and CC	294	437	1.13	(0.90-1.42)	1.11	(0.88-1.41)	1.12	(0.88-1.42)	0.35
IL-10 C-592A (rs1800872)
CC	328	483	1.00	-	1.00	-	1.00	-
AC	149	261	0.84	(0.66-1.07)	0.83	(0.65-1.07)	0.83	(0.64-1.07)	0.14
AA	21	35	0.88	(0.51-1.55)	0.99	(0.56-1.76)	1.00	(0.56-1.77)	0.99
AC and AA	170	296	0.85	(0.67-1.07)	0.85	(0.67-1.08)	0.85	(0.66-1.08)	0.18
IL-10 C-819T (rs1800871)
CC	325	483	1.00	-	1.00	-	1.00	-
CT	151	259	0.87	(0.68-1.11)	0.86	(0.67-1.11)	0.85	(0.66-1.10)	0.22
TT	22	37	0.88	(0.51-1.53)	1.00	(0.57-1.74)	1.00	(0.57-1.75)	0.99
CT and TT	173	296	0.87	(0.69-1.10)	0.88	(0.69-1.12)	0.87	(0.68-1.11)	0.27
IL-10 G-1082A (rs1800896)
GG	169	238	1.00	-	1.00	-	1.00	-
AG	239	374	0.90	(0.70-1.16)	0.91	(0.70-1.19)	0.93	(0.72-1.22)	0.61
AA	90	167	0.76	(0.55-1.05)	0.78	(0.56-1.08)	0.76	(0.54-1.06)	0.10
AG and AA	329	541	0.86	(0.67-1.09)	0.87	(0.68-1.12)	0.88	(0.68-1.13)	0.31
(rs3024505)
CC	297	522	1.00	-	1.00	-	1.00	-
CT	172	235	1.29	(1.01-1.64)	1.35	(1.05-1.73)	1.34	(1.04-1.73)	0.02
TT	29	22	2.32	(1.31-4.11)	2.37	(1.31-4.29)	2.31	(1.27-4.20)	0.01
CT and TT	201	779	1.37	(1.09-1.74)	1.43	(1.13-1.83)	1.43	(1.12-1.82)	0.004
HO-1 A-413T (rs2071746)
AA	162	267	1.00	-	1.00	-	1.00	-
AT	251	373	1.11	(0.86-1.43)	1.10	(0.85-1.42)	1.11	(0.85-1.44)	0.45
TT	85	139	1.01	(0.72-1.41)	1.00	(0.71-1.41)	1.01	(0.71-1.42)	0.98
AT and TT	336	512	1.08	(0.85-1.37)	1.07	(0.84-1.37)	1.08	(0.84-1.38)	0.55

ISSN: 1471-2350