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Table 3 Genotypes in Danish patients with ulcerative colitis1.

From: The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

  Ncase Ncontrol OR (95%CI)2 OR (95%CI)3 OR (95%CI)4 P-value5
IL1 β C-31T (rs1143627)          
   TT 204 342 1.00 - 1.00 - 1.00 -  
   CT 238 342 1.17 (0.92-1.48) 1.15 (0.90-1.47) 1.15 (0.89-1.47) 0.28
   CC 56 95 0.99 (0.68-1.43) 0.99 (0.68-1.46) 1.02 (0.69-1.49) 0.94
   CT and CC 294 437 1.13 (0.90-1.42) 1.11 (0.88-1.41) 1.12 (0.88-1.42) 0.35
IL-10 C-592A (rs1800872)          
   CC 328 483 1.00 - 1.00 - 1.00 -  
   AC 149 261 0.84 (0.66-1.07) 0.83 (0.65-1.07) 0.83 (0.64-1.07) 0.14
   AA 21 35 0.88 (0.51-1.55) 0.99 (0.56-1.76) 1.00 (0.56-1.77) 0.99
   AC and AA 170 296 0.85 (0.67-1.07) 0.85 (0.67-1.08) 0.85 (0.66-1.08) 0.18
IL-10 C-819T (rs1800871)          
   CC 325 483 1.00 - 1.00 - 1.00 -  
   CT 151 259 0.87 (0.68-1.11) 0.86 (0.67-1.11) 0.85 (0.66-1.10) 0.22
   TT 22 37 0.88 (0.51-1.53) 1.00 (0.57-1.74) 1.00 (0.57-1.75) 0.99
   CT and TT 173 296 0.87 (0.69-1.10) 0.88 (0.69-1.12) 0.87 (0.68-1.11) 0.27
IL-10 G-1082A (rs1800896)          
   GG 169 238 1.00 - 1.00 - 1.00 -  
   AG 239 374 0.90 (0.70-1.16) 0.91 (0.70-1.19) 0.93 (0.72-1.22) 0.61
   AA 90 167 0.76 (0.55-1.05) 0.78 (0.56-1.08) 0.76 (0.54-1.06) 0.10
   AG and AA 329 541 0.86 (0.67-1.09) 0.87 (0.68-1.12) 0.88 (0.68-1.13) 0.31
(rs3024505)          
   CC 297 522 1.00 - 1.00 - 1.00 -  
   CT 172 235 1.29 (1.01-1.64) 1.35 (1.05-1.73) 1.34 (1.04-1.73) 0.02
   TT 29 22 2.32 (1.31-4.11) 2.37 (1.31-4.29) 2.31 (1.27-4.20) 0.01
   CT and TT 201 779 1.37 (1.09-1.74) 1.43 (1.13-1.83) 1.43 (1.12-1.82) 0.004
HO-1 A-413T (rs2071746)          
   AA 162 267 1.00 - 1.00 - 1.00 -  
   AT 251 373 1.11 (0.86-1.43) 1.10 (0.85-1.42) 1.11 (0.85-1.44) 0.45
   TT 85 139 1.01 (0.72-1.41) 1.00 (0.71-1.41) 1.01 (0.71-1.42) 0.98
   AT and TT 336 512 1.08 (0.85-1.37) 1.07 (0.84-1.37) 1.08 (0.84-1.38) 0.55
  1. 1OR = Odds Ratio, 95%CI = 95% confidence interval,
  2. 2 Crude,
  3. 3 Adjusted for age and gender,
  4. 4 Adjusted for age, gender and smoking status.
  5. 5P for the fully adjusted estimate